BDBM50461386 CHEMBL4225828
SMILES CNC(=O)c1ccc(Sc2cccc(NC(=S)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)nc1
InChI Key InChIKey=QMRSZKRJQUFALC-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50461386
Affinity DataIC50: 596nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of B-Raf (unknown origin) using MEK1 as substrate measured after 2 hrs by ELISAMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of VEGFR2 (unknown origin) using FAM-labelled peptide as substrate pretreated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Yantai University
Curated by ChEMBL
Yantai University
Curated by ChEMBL
Affinity DataIC50: 781nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 as substrate measured after 2 hrs by ELISAMore data for this Ligand-Target Pair