BDBM50485023 CHEMBL2023340
SMILES CCCS(=O)(=O)Nc1ccc(F)c(c1F)-c1cc2cnc(N)nc2n(C)c1=O
InChI Key InChIKey=QOMAVDVRJHWHNF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50485023
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length B-Raf V600E mutant assessed as reduction in incorporation of radiolabeled phosphate from [gamma-33P]ATP into FSBA-modified ...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of full-length B-Raf V600E mutant in human MALME-3M cells assessed as reduction in basal ERK1/2 phosphorylation incubated for 1 hrMore data for this Ligand-Target Pair