BDBM50493386 CHEMBL2425737
SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)CCOc4ccccc4)cc23)c1
InChI Key InChIKey=FCAVKAMZQCESHE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50493386
Affinity DataIC50: 19nMAssay Description:Inhibition of wild type human EGFR tyrosine kinase assessed as Ulight-CAGAGAIETDKEYYTVKD phosphorylation after 15 mins by time-resolved fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured after 8 hrs by Western ...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured at 1 hr by Western blot...More data for this Ligand-Target Pair