BDBM50494960 CHEMBL3099430::US10570077, Compound 7

SMILES [H][C@@]12CC=C([C@@H](C)CC)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]

InChI Key InChIKey=LHXJYHZPNIJDNM-DZIGDOIQSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50494960   

TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

US Patent
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataKd:  160nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at ERbeta (unknown origin) assessed as inhibition of E2-induced receptor activation after 22 hrs by cell-based luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataIC50:  88nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

US Patent
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataKd:  160nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed