BDBM50522404 CHEMBL4562350

SMILES Nc1nc2ccc(SCc3ccc(cc3)C(=O)NCc3ccccc3)cc2s1

InChI Key InChIKey=SHIMUUKQGMXWNC-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50522404   

TargetCytochrome P450 1A2(Homo sapiens (Human))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus infected insect cells using beetle D-luciferin as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of Leishmania major pteridine reductase 1 using di-hydrobiopterine as substrate in presence of NADPHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50522404(CHEMBL4562350)
Affinity DataIC50: >2.50E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed