BDBM50526788 CHEMBL4471850

SMILES CC(C)c1cnn2c(NCc3ccccc3)cc(NC[C@]3(O)CCNC[C@H]3O)nc12

InChI Key InChIKey=OVDMCYNLHNMECD-XMSQKQJNSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50526788   

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526788(CHEMBL4471850)
Affinity DataIC50:  18nMAssay Description:Inhibition of CDK7/CycH/MAT1 (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526788(CHEMBL4471850)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of CDK1 (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Tianjin University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50526788(CHEMBL4471850)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of CDK2/cycE1 (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed