BDBM50564376 CHEMBL4781229::US11370779, Compound 4
SMILES COC(=O)c1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\OCCN3CCNCC3)c2c1
InChI Key InChIKey=HHKOKFHTWVYTJK-NXGRKYSHSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50564376
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human FLT3 using peptide substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The inhibition of the FLT3 kinase activity was measured with homogeneous, time-resolved fluorescence (HTRF) assays. Recombinant proteins containing t...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Zunyi Medical University
Curated by ChEMBL
Zunyi Medical University
Curated by ChEMBL
Affinity DataIC50: 239nMAssay Description:Inhibition of c-met (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Gwangju Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 523nMAssay Description:Inhibition of recombinant JAK2 (unknown origin)More data for this Ligand-Target Pair