BDBM50600301 CHEMBL5178312

SMILES COc1ccc(cc1)C1(CCCC1)C(=O)N1CCC[C@@H]1C(=O)Nc1cccc2[nH]ncc12

InChI Key InChIKey=KRGAGJKQQRBFEC-JOCHJYFZSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600301   

TargetHistone acetyltransferase p300(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600301(CHEMBL5178312)
Affinity DataIC50:  690nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50600301(CHEMBL5178312)
Affinity DataIC50:  180nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair