BDBM5810 N-{3-[4-amino-5-(4-phenylphenyl)furo[2,3-d]pyrimidin-6-yl]phenyl}methanesulfonamide::furo[2,3-d]pyrimidine deriv. 7f

SMILES CS(=O)(=O)Nc1cccc(c1)-c1oc2ncnc(N)c2c1-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YPTADYIVARXAPS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 5810   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5810(N-{3-[4-amino-5-(4-phenylphenyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5810(N-{3-[4-amino-5-(4-phenylphenyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  191nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dalian University

Curated by ChEMBL
LigandPNGBDBM5810(N-{3-[4-amino-5-(4-phenylphenyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  36.3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dalian University

Curated by ChEMBL
LigandPNGBDBM5810(N-{3-[4-amino-5-(4-phenylphenyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  36nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed