BDBM6647 3-(7-hydroxynaphthalen-1-yl)-1-pyridin-3-ylurea::Diarylurea deriv. 1b::N-(7-Hydroxy-1-naphthyl)-N -pyridin-3-ylurea

SMILES Oc1ccc2cccc(NC(=O)Nc3cccnc3)c2c1

InChI Key InChIKey=ZTWGCHGNQQVQSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6647   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute

LigandPNGBDBM6647(3-(7-hydroxynaphthalen-1-yl)-1-pyridin-3-ylurea | ...)
Affinity DataIC50:  3.40E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed