BDBM716457 US20250034112, Compound 33b

SMILES N#Cc1ccc(Nc2nc(N)nc(Oc3cccc(C(=O)O)c3)n2)cc1

InChI Key InChIKey=WKFGNLUJVJDVRJ-UHFFFAOYSA-N

Data  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716457   

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Yale University

US Patent
LigandPNGBDBM716457(US20250034112, Compound 33b)
Affinity DataKd:  3.96E+4nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)