BDBM7683 4-({1-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]ethyl}amino)benzene-1-sulfonamide::4-{[1-(2-Oxo-1,2-dihydro-3H-indol-3-ylidene)ethyl]-amino}benzenesulfonamide::Oxindole-Based Inhibitor 19

SMILES CC(=Nc1ccc(cc1)S(N)(=O)=O)C1C(=O)Nc2ccccc12

InChI Key InChIKey=DUGPEYYCVBKDIP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7683   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7683(4-({1-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]e...)
Affinity DataIC50:  2.30E+3nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7683(4-({1-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]e...)
Affinity DataIC50:  360nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7683(4-({1-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]e...)
Affinity DataIC50:  360nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7683(4-({1-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]e...)
Affinity DataIC50:  360nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7683(4-({1-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]e...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed