BDBM86219 CAS_5537::NSC_5537::Trequinsin

SMILES COc1cc2CCn3c(cc(=Nc4c(C)cc(C)cc4C)n(C)c3=O)-c2cc1OC

InChI Key InChIKey=MCMSJVMUSBZUCN-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86219   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
University of Tennessee

Curated by PDSP Ki Database
LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataKi:  3.15E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
University of Tennessee

Curated by PDSP Ki Database
LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
University of North Carolina

LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataIC50:  3.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed