BDBM8936 6-(1H-imidazol-5-ylmethyl)-5-methyl-7,8-dihydronaphthalen-2-ol::BW19 analog 1::dihydronaphthalene derivative

SMILES CC1=C(Cc2cnc[nH]2)CCc2cc(O)ccc12

InChI Key InChIKey=QCJQPRFLMJEUJL-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8936   

TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8936(6-(1H-imidazol-5-ylmethyl)-5-methyl-7,8-dihydronap...)
Affinity DataIC50:  2.30E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H]androstenedione during aromatization. After incubation, the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8936(6-(1H-imidazol-5-ylmethyl)-5-methyl-7,8-dihydronap...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed