BDBM8956 1-[(2,3,4-trimethoxy-1,1-biphenyl-4-yl)methyl]-1H-imidazole::1-{[4-(2,3,4-trimethoxyphenyl)phenyl]methyl}-1H-imidazole::methyl imidazole biphenyl derivative 19

SMILES COc1ccc(c(OC)c1OC)-c1ccc(Cn2ccnc2)cc1

InChI Key InChIKey=FKNKXRIEZUMVKB-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8956   

TargetAromatase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8956(1-[(2,3,4-trimethoxy-1,1-biphenyl-4-yl)methyl]-1H-...)
Affinity DataIC50:  7.70E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H]androstenedione during aromatization. After incubation, the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8956(1-[(2,3,4-trimethoxy-1,1-biphenyl-4-yl)methyl]-1H-...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed