2OHT: X-ray crystal structure of beta secretase complexed with compound 7

PDB ID: 2OHTDownload
MMDB ID: 45211
PDB Deposition Date: 2007/1/10
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2OHT: monomeric; determined by author
Molecular Components in 2OHT
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
IODIDE IONIODIDE ION
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINEN~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303