3QX3: Human topoisomerase IIbeta in complex with DNA and etoposide

PDB ID: 3QX3Download
MMDB ID: 91380
PDB Deposition Date: 2011/3/1
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.162  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3QX3: hexameric; determined by author and by software (PISA)
Molecular Components in 3QX3
Label Count Molecule
Proteins (2 molecules)
2
DNA Topoisomerase 2-beta
Molecule annotation
Nucleotides(4 molecules)
2
DNA (5'-d(p*ap*gp*cp*cp*gp*ap*gp*c)-3')
Molecule annotation
2
DNA (5'-d(p*tp*gp*cp*ap*gp*cp*tp*cp*gp*gp*cp*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
2
6
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303