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3FL8:
Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative
PDB ID:
3FL8
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MMDB ID:
71399
PDB Deposition Date:
2008/12/18
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.2881 Å
Source Organism:
Bacillus anthracis
Similar Structures:
VAST+
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Biological Unit for 3FL8: monomeric; determined by author and by software (PISA)
Molecular Components in 3FL8
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CALCIUM ION
2
1
5-(3,4-dimethoxy-5-{(1E)-3-oxo-3-[(1S)-1-propylphthalazin-2(1H)-yl]prop-1-en-1-yl}benzyl)pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303