NCBI
National Center for
Biotechnology Information
Search
3QBH:
Structure Based Design, Synthesis And Sar Of Cyclic Hydroxyethylamine (hea) Bace-1 Inhibitors
PDB ID:
3QBH
Download
MMDB ID:
89415
PDB Deposition Date:
2011/1/13
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.24 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3QBH: monomeric; determined by author and by software (PISA)
Molecular Components in 3QBH
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4s)-4-(2-Hydroxy-5-{[(3s,4s,5r)-4-Hydroxy-1,1-Dioxido-5-{[3-(Propan-2-Yl)benzyl]amino}tetrahydro-2h-Thiopyran-3-Yl]methyl}benzyl)-3-Propyl-1,3-Oxazolidin-2-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303