4HBV: Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand

PDB ID: 4HBVDownload
MMDB ID: 104646
PDB Deposition Date: 2012/9/28
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 4HBV: monomeric; determined by author and by software (PISA)
Molecular Components in 4HBV
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
6-bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one6-bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303