TargetCytochrome P450 2D6(Homo sapiens (Human))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human microsomal CYP2D6 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human microsomal CYP2C19 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pr...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human microsomal CYP2C9 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human microsomal CYP3A4 expressed in baculovirus infected BTI-TN-5B1-4 cell microsomes using CYP/Luciferin as substrate pre...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Modena and Reggio Emilia
Curated by ChEMBL
University of Modena and Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 600nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af...More data for this Ligand-Target Pair
Affinity DataKd: 4.70E+3nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af...More data for this Ligand-Target Pair
Affinity DataKd: 280nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af...More data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af...More data for this Ligand-Target Pair
Affinity DataKd: 6.30E+3nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af...More data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af...More data for this Ligand-Target Pair
Affinity DataKd: 3.30E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 1.90E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 3.40E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 1.50E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 3.80E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 2.70E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
Affinity DataKd: 9.00E+3nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+4nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 8.00E+3nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+4nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 4.00E+3nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant aft...More data for this Ligand-Target Pair
Affinity DataKd: 1.20E+4nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Displacement of [3H]-R-PIA from adenosine A1 receptor (unknown origin) expressed in sheep striatum membranes after 2 hrs by scintillation counting an...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 4.40E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 3.70E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 6.00E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 1.80E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 2.60E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
Affinity DataKd: 2.70E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair