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Found 33 with Last Name = 'vieira da cruz' and Initial = 'a'
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataKi:  3.10E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  3.40E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583381(CHEMBL5029066 | US20230339856, Compound (IIb1))
Affinity DataKi:  6.40E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628473(US20230339856, Compound (IIc))
Affinity DataKi:  7.60E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583383(CHEMBL5028005 | US20230339856, Compound (IIb3))
Affinity DataKi:  1.08E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583379(CHEMBL5028138 | US20230339856, Compound (IIb))
Affinity DataKi:  1.30E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628488(US20230339856, Compound (IIc1))
Affinity DataKi:  1.30E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628474(US20230339856, Compound (IId))
Affinity DataKi:  1.89E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628489(US20230339856, Compound (IIr))
Affinity DataKi:  2.00E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628474(US20230339856, Compound (IId))
Affinity DataIC50:  150nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628473(US20230339856, Compound (IIc))
Affinity DataIC50:  220nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583379(CHEMBL5028138 | US20230339856, Compound (IIb))
Affinity DataIC50:  390nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  410nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583378(CHEMBL5028084 | US20230339856, Compound (IIa))
Affinity DataIC50:  420nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50:  460nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628475(US20230339856, Compound (IIf))
Affinity DataIC50:  870nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628478(US20230339856, Compound (IIh))
Affinity DataIC50:  9.70E+3nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628480(US20230339856, Compound (IIk))
Affinity DataIC50:  1.16E+4nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628479(US20230339856, Compound (IIj))
Affinity DataIC50:  1.52E+4nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628482(US20230339856, Compound (IIn))
Affinity DataIC50:  2.46E+4nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628489(US20230339856, Compound (IIr))
Affinity DataIC50:  2.95E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583383(CHEMBL5028005 | US20230339856, Compound (IIb3))
Affinity DataIC50:  2.96E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628486(US20230339856, Compound (IIb7))
Affinity DataIC50:  3.16E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628488(US20230339856, Compound (IIc1))
Affinity DataIC50:  3.29E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628473(US20230339856, Compound (IIc))
Affinity DataIC50:  3.72E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628485(US20230339856, Compound (IIx1))
Affinity DataIC50:  4.03E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628481(US20230339856, Compound (IIm))
Affinity DataIC50:  4.50E+4nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583381(CHEMBL5029066 | US20230339856, Compound (IIb1))
Affinity DataIC50:  4.91E+4nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583379(CHEMBL5028138 | US20230339856, Compound (IIb))
Affinity DataIC50:  1.04E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628474(US20230339856, Compound (IId))
Affinity DataIC50:  1.82E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM628475(US20230339856, Compound (IIf))
Affinity DataIC50:  2.97E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50583378(CHEMBL5028084 | US20230339856, Compound (IIa))
Affinity DataIC50:  3.41E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50:  3.87E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent