Affinity DataKi: 180nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5.70E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.70E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 9.90E+3nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.90E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]ezetimibe-glucuronide from NPC1L1 in Sprague-Dawley rat brush border membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMpH: 7.2 T: 2°CAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair