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Found 20 with Last Name = 'renga' and Initial = 'b'
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50011369(CHEMBL3260994)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of human FXR transfected in human HepG2 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50351162(CHEMBL1818098 | CHEMBL1818099)
Affinity DataEC50:  2.40E+4nMAssay Description:Antagonist activity at FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as inhibition of CDCA-induced transactivation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50028026(CHEMBL3342065)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells assessed as receptor transactivation at 100 nM to 50 uM incubated for 16 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50028027(CHEMBL3342086)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at FXR (unknown origin) expressed in human HepG2 cells assessed as receptor transactivation at 100 nM to 50 uM incubated for 16 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50028028(CHEMBL3342082)
Affinity DataEC50:  1.03E+3nMAssay Description:Agonist activity at GP-BAR1 (unknown origin) in human HEK293 cells assessed as receptor transactivation at 100 nM to 50 uM incubated for 16 hrs by CR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50028027(CHEMBL3342086)
Affinity DataEC50:  400nMAssay Description:Agonist activity at GP-BAR1 (unknown origin) in human HEK293 cells assessed as receptor transactivation at 100 nM to 50 uM incubated for 16 hrs by CR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50098804(CHEMBL3329940)
Affinity DataEC50:  2.44E+4nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293T cells assessed as stimulation of cAMP response element-mediated receptor transactivation by luc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50098805(CHEMBL3330019)
Affinity DataEC50:  1.72E+4nMAssay Description:Agonist activity at human GPBAR1 expressed in HEK293T cells assessed as stimulation of cAMP response element-mediated receptor transactivation by luc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universita Di Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50347619(CHEMBL1649712 | Solomonsterol A)
Affinity DataEC50:  5.20E+3nMAssay Description:Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universita Di Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50347620(RIFAXIMIN | Rifacol | Rifaxidin)
Affinity DataEC50:  2.20E+3nMAssay Description:Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataEC50:  100nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50398351(CHEMBL2178583)
Affinity DataEC50:  1.00E+4nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50398352(CHEMBL2178586)
Affinity DataEC50:  2.00E+3nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50398353(CHEMBL2178596)
Affinity DataEC50:  5.00E+3nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universita Di Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50448129(CHEMBL3122144)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universita Di Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50347620(RIFAXIMIN | Rifacol | Rifaxidin)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universita Di Napoli Federico Ii

Curated by ChEMBL
LigandPNGBDBM50448128(CHEMBL3122141)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50434773(CHEMBL2386488)
Affinity DataEC50:  3.00E+4nMAssay Description:Transactivation of FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as beta-galactosidase activity after 18 hrs by luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50434774(CHEMBL2386485)
Affinity DataEC50:  2.50E+4nMAssay Description:Antagonist activity at FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as inhibition of CDCA-induced transactivation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50011369(CHEMBL3260994)
Affinity DataEC50:  200nMAssay Description:Transactivation of human GP-BAR1 transfected in HEK293T cells assessed as induction of intracellular cAMP production after 18 hrs by cAMP responsive ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed