Affinity DataKi: <0.0100nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:The compound was evaluated for inhibition of HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Compound was evaluated for inhibition of S. cerevisiae glyoxalase-I by using enzymatic assay at each of 6 substrate concentrations between 0.1 mM and...More data for this Ligand-Target Pair
Affinity DataKi: <0.0100nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0160nM ΔG°: -64.1kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0160nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:The compound was evaluated for inhibition of HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:Compound was evaluated for inhibition of HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0210nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0240nM ΔG°: -63.1kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0260nM ΔG°: -62.8kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0270nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity for HIV -1 ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0340nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0350nM ΔG°: -62.1kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0370nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0380nM ΔG°: -61.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0380nM ΔG°: -61.9kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0410nMAssay Description:The compound was evaluated for inhibition of HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0460nM ΔG°: -61.4kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0470nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0580nMAssay Description:Binding affinity for HIV -1 ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0590nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0590nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0610nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0610nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0620nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0670nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0670nMAssay Description:Tested for inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0680nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0680nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.0690nM ΔG°: -60.3kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.0710nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0720nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0780nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:The compound was evaluated for inhibition of HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity for HIV -1 ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0940nMAssay Description:Binding affinity of the compound against HIV-Protease was determinedMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.110nM ΔG°: -59.1kJ/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:HIV protease inhibition.More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Binding affinity for HIV -1 ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibitory activity was evaluated against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Binding affinity for HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Binding affinity for HIV -1 ProteaseMore data for this Ligand-Target Pair