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Found 63 with Last Name = 'farrer' and Initial = 'bt'
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239050(CHEMBL4079100)
Affinity DataEC50:  28nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239042(CHEMBL4094511)
Affinity DataEC50:  728nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM260387(US9527838, 15)
Affinity DataEC50:  69nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM260389(US9527838, 17)
Affinity DataEC50:  49nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM260385(US9527838, 13)
Affinity DataEC50:  5.70nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM260383(US9527838, 11)
Affinity DataEC50:  14nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM260404(US9527838, 32)
Affinity DataEC50:  9.60nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239040(CHEMBL4086771)
Affinity DataEC50:  5.5nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239042(CHEMBL4094511)
Affinity DataEC50:  24nMAssay Description:Ability to displace [3H]spiperone binding from anterior pituitary Dopamine receptor D2 in the presence of 100 uM GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239043(CHEMBL4067037)
Affinity DataEC50:  4.80nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  8.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50:  86nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50:  86nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  31nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239047(CHEMBL4078915)
Affinity DataEC50:  48nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239040(CHEMBL4086771)
Affinity DataEC50:  5.5nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  4.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  4.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  0.900nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  0.900nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239040(CHEMBL4086771)
Affinity DataEC50:  21nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239040(CHEMBL4086771)
Affinity DataEC50:  21nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239047(CHEMBL4078915)
Affinity DataEC50:  7.20nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  3.90nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  3.90nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50:  2.5nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  7.80nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239049(CHEMBL4086782)
Affinity DataEC50:  1.70nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239043(CHEMBL4067037)
Affinity DataEC50:  22nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  7.5nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  7.5nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239040(CHEMBL4086771)
Affinity DataEC50:  16nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239047(CHEMBL4078915)
Affinity DataEC50:  23nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239047(CHEMBL4078915)
Affinity DataEC50:  23nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  5.20nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50:  2.70nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50:  2.70nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239049(CHEMBL4086782)
Affinity DataEC50:  174nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239043(CHEMBL4067037)
Affinity DataEC50:  232nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239043(CHEMBL4067037)
Affinity DataEC50:  9.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239049(CHEMBL4086782)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  3.40nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50: <0.850nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  9.80nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239046(CHEMBL4068048)
Affinity DataEC50:  9.80nMAssay Description:Inhibition of cGMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239047(CHEMBL4078915)
Affinity DataEC50:  18nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239040(CHEMBL4086771)
Affinity DataEC50:  1nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of cAMP PDE II enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239048(CHEMBL4067028)
Affinity DataEC50:  0.800nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239045(CHEMBL4083339)
Affinity DataEC50:  31nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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