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Found 301 with Last Name = 'markert' and Initial = 'c'
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212110(US9290485, 142)
Affinity DataIC50:  0.0224nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212116(US9290485, 148)
Affinity DataIC50:  0.0300nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212114(US9290485, 146)
Affinity DataIC50:  0.0400nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM211977(US9290485, 9)
Affinity DataIC50:  0.0912nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212115(US9290485, 147)
Affinity DataIC50:  0.100nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212136(US9290485, 168)
Affinity DataIC50:  0.100nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212004(US9290485, 36)
Affinity DataIC50:  0.134nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM211974(US9290485, 6)
Affinity DataIC50:  0.200nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212134(US9290485, 166)
Affinity DataIC50:  0.200nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212135(US9290485, 167)
Affinity DataIC50:  0.200nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212113(US9290485, 145)
Affinity DataIC50:  0.200nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212141(US9290485, 173)
Affinity DataIC50:  0.400nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212124(US9290485, 156)
Affinity DataIC50:  0.920nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212109(US9290485, 141)
Affinity DataIC50:  1.20nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575492(CHEMBL4784496)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212125(US9290485, 157)
Affinity DataIC50:  2nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212122(US9290485, 154)
Affinity DataIC50:  2nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212062(US9290485, 94)
Affinity DataIC50:  2.10nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212111(US9290485, 143)
Affinity DataIC50:  2.60nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575479(CHEMBL4878813)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575478(CHEMBL4858542)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575477(CHEMBL4859847)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212123(US9290485, 155)
Affinity DataIC50:  3nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212137(US9290485, 169)
Affinity DataIC50:  3nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575487(CHEMBL4871560)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575486(CHEMBL4857223)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575485(CHEMBL4846099)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575481(CHEMBL4866709)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575482(CHEMBL4870263)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575483(CHEMBL4869350)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575484(CHEMBL4847272)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212043(US9290485, 75)
Affinity DataIC50:  3.10nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212083(US9290485, 115)
Affinity DataIC50:  3.30nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575489(CHEMBL4871711)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575465(CHEMBL4851581)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575488(CHEMBL4852381)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of LTA4H in human PBMC assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed by ion...More data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212129(US9290485, 161)
Affinity DataIC50:  4nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575468(CHEMBL4879150)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212126(US9290485, 158)
Affinity DataIC50:  4nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212120(US9290485, 152)
Affinity DataIC50:  4nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575480(CHEMBL4849465)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212108(US9290485, 140)
Affinity DataIC50:  4.60nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575493(Acebilustat | Ctx-4430 | EP-501)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212107(US9290485, 139)
Affinity DataIC50:  4.90nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212130(US9290485, 162)
Affinity DataIC50:  5nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212131(US9290485, 163)
Affinity DataIC50:  5nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212057(US9290485, 89)
Affinity DataIC50:  6nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212133(US9290485, 165)
Affinity DataIC50:  6nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in ⿿assay buffer⿿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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