Affinity DataKi: 330nMAssay Description:Inhibition of human neurokinin NK2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Inhibition of human histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reductionMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity at rat recombinant GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated LH release from rat pituitary cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair