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Found 171 with Last Name = 'evans' and Initial = 'ce'
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndoplasmin(Canis familiaris)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20732((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...)
Affinity DataIC50:  10nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50439621(GANETESPIB | STA-9090)
Affinity DataIC50:  10nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  12nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targeto-succinylbenzoate synthase(Escherichia coli K-12 (Enterobacteria))
Argonne National Laboratory

LigandPNGBDBM181038(OSB-AMS (1))
Affinity DataIC50:  25nMpH: 7.4Assay Description:Enzyme inhibition studies were performed in 20 mM NaHPO4 buffer (pH 7.4) containing 150 mM NaCl and 1 mM MgCl2 using a MenE-MenB coupled assay in whi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50180302(8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isop...)
Affinity DataIC50:  30nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataIC50:  31nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  38nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50439621(GANETESPIB | STA-9090)
Affinity DataIC50:  51nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 21: This assay is based on a competitive binder which can interact with a latent pocket formed only in the inactive state of the kinase. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of Tyrosine-protein kinase Fyn (T)(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 22: This assay referred to as FlashPlate-based Protein Kinase Assay uses recombinant protein kinase and ATP concentration corresponding to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473176(US10844038, Example 37 | US10844038, Example 38 | ...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50: Methods for In Vitro Evaluation Assays known in the art for testing compounds are used to test compounds of this invention and to assess the bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473184(US10844038, Example 62 | trans 3-((4-Amino-3-(4-(2...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473185(US10844038, Example 63 | trans 3-((4-Amino-3-(4-(2...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn [Y531F](Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn [Y531F](Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473175((3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn [Y531F](Homo sapiens (Human))
Sabila Biosciences

US Patent
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50:  52nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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