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Found 51 with Last Name = 'de souza' and Initial = 'df'
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193512(CHEMBL3931628)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193539(CHEMBL3906729)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193537(CHEMBL3924713)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193532(CHEMBL3897721)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193530(CHEMBL3907702)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193533(CHEMBL3925612)
Affinity DataIC50:  7nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193529(CHEMBL3950031)
Affinity DataIC50:  8nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193541(CHEMBL3970840)
Affinity DataIC50:  12nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193528(CHEMBL3979082)
Affinity DataIC50:  23nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193514(CHEMBL3897530)
Affinity DataIC50:  28nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193514(CHEMBL3897530)
Affinity DataIC50:  30nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193534(CHEMBL3934708)
Affinity DataIC50:  32nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193531(CHEMBL3932283)
Affinity DataIC50:  37nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193534(CHEMBL3934708)
Affinity DataIC50:  39nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193529(CHEMBL3950031)
Affinity DataIC50:  47nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193531(CHEMBL3932283)
Affinity DataIC50:  48nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193530(CHEMBL3907702)
Affinity DataIC50:  52nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193541(CHEMBL3970840)
Affinity DataIC50:  52nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193535(CHEMBL3925814)
Affinity DataIC50:  54nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193532(CHEMBL3897721)
Affinity DataIC50:  65nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193528(CHEMBL3979082)
Affinity DataIC50:  82nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193537(CHEMBL3924713)
Affinity DataIC50:  87nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193533(CHEMBL3925612)
Affinity DataIC50:  108nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  114nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193539(CHEMBL3906729)
Affinity DataIC50:  116nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193535(CHEMBL3925814)
Affinity DataIC50:  132nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193512(CHEMBL3931628)
Affinity DataIC50:  156nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193513(CHEMBL3964439)
Affinity DataIC50:  452nMAssay Description:Inhibition of Wistar rat brain AChE using acetylthiochloline iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50193513(CHEMBL3964439)
Affinity DataIC50:  456nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544190(CHEMBL4642912)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544189(CHEMBL4638488)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544187(CHEMBL4633659)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544193(CHEMBL1540399)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544183(CHEMBL4647549)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544188(CHEMBL4643280)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544184(CHEMBL4638799)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544195(CHEMBL4639355)
Affinity DataIC50:  8.10E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM38964(3-[(4-methoxyphenoxy)methyl]benzoic acid | MLS0000...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544191(CHEMBL4635914)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544186(CHEMBL4638822)
Affinity DataIC50:  1.52E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544192(CHEMBL4644947)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544182(CHEMBL4649874)
Affinity DataIC50:  2.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50508821(CHEMBL4443020)
Affinity DataIC50:  4.42E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544194(CHEMBL4634216)
Affinity DataIC50:  4.54E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544185(CHEMBL4638943)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Mycobacterium tuberculosis)
University Hospital T£Bingen

Curated by ChEMBL
LigandPNGBDBM50544196(CHEMBL4637819)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis DHFR expressed in Escherichia coli BL21(DE3) cells using DHF as substrate and NADPH as cofactor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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