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Found 628 with Last Name = 'lassalle' and Initial = 'g'
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM7840(RIVAROXABAN | US8822458, 44 | US8822458, 97)
Affinity DataKi:  0.400nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of t-PA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443855(CHEMBL3091517)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443857(CHEMBL3091501)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443846(CHEMBL3091527)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443858(CHEMBL3091502)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443847(CHEMBL3091526)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50100263(CHEMBL3326907)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443861(CHEMBL3091515)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443844(CHEMBL3091506)
Affinity DataIC50:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443869(CHEMBL3091507)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443848(CHEMBL3091525)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443862(CHEMBL3091514)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443867(CHEMBL3091509)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443865(CHEMBL3091511)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183069(US9150544, 103)
Affinity DataIC50:  1.40nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443864(CHEMBL3091512)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188704(US9169246, 246)
Affinity DataIC50:  1.46nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443845(CHEMBL3091528)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443856(CHEMBL3091503)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443866(CHEMBL3091510)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182990(US9150544, 24)
Affinity DataIC50:  2nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188545(US9169246, 30)
Affinity DataIC50:  2.13nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443860(CHEMBL3091505)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50328705(CHEMBL1270156 | Tanogitran)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of factor-10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443863(CHEMBL3091513)
Affinity DataIC50:  3nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188567(US9169246, 66)
Affinity DataIC50:  3.06nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443868(CHEMBL3091508)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443859(CHEMBL3091504)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188731(US9169246, 273)
Affinity DataIC50:  3.45nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188706(US9169246, 248)
Affinity DataIC50:  3.87nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188541(US9169246, 19)
Affinity DataIC50:  3.94nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM182980(US9150544, 14)
Affinity DataIC50:  4nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188569(US9169246, 68)
Affinity DataIC50:  4.12nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188707(US9169246, 249)
Affinity DataIC50:  4.19nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188621(US9169246, 121)
Affinity DataIC50:  4.29nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188708(US9169246, 250)
Affinity DataIC50:  4.41nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188686(US9169246, 226)
Affinity DataIC50:  4.68nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188659(US9169246, 199)
Affinity DataIC50:  4.90nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188693(US9169246, 235)
Affinity DataIC50:  4.99nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM183016(US9150544, 50)
Affinity DataIC50:  5nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50100269(CHEMBL3325627)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188692(US9169246, 234)
Affinity DataIC50:  5.33nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188709(US9169246, 251)
Affinity DataIC50:  5.34nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188571(US9169246, 70)
Affinity DataIC50:  5.62nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM188728(US9169246, 270)
Affinity DataIC50:  6nMAssay Description:The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...More data for this Ligand-Target Pair
In DepthDetails US Patent
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