Compile Data Set for Download or QSAR
maximum 50k data
Found 111 with Last Name = 'kraus' and Initial = 'h'
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412955(CHEMBL407706)
Affinity DataKi: <3.16E+3nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50478241(CHEMBL256263)
Affinity DataKi: <3.16E+3nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50471425(CHEMBL110041)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50471426(CHEMBL110367)
Affinity DataIC50:  2.05E+5nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50:  2.23E+5nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50471428(CHEMBL111794)
Affinity DataIC50: >9.58E+5nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50471424(CHEMBL109814)
Affinity DataIC50: >1.10E+6nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50471423(CHEMBL322103)
Affinity DataIC50:  1.36E+6nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50471427(CHEMBL113127)
Affinity DataIC50: >1.38E+6nMAssay Description:Inhibition of supercoiling activity of DNA gyrase in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283057((1R,5S,6R,7R)-6-((Z)-7-Hydroxy-hept-2-enyl)-7-((E)...)
Affinity DataEC50:  1nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283058((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  324nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283059((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  24nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by aggregation of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283060((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  3.11E+3nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by aggregation of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283059((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  0.230nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283060((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  58nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282691(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  1.40nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282692(4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  11nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  5nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282693(4-[(E)-2-(3-Chloro-5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  275nMAssay Description:Transcriptional activation for RXR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032221(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  4.58E+3nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  0.5nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticleMMDB

TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  24nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  3.30nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282694(4-[(E)-2-(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  91nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282694(4-[(E)-2-(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  298nMAssay Description:Transcriptional activation for RXR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032221(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  74nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  2.40nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282693(4-[(E)-2-(3-Chloro-5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  77nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282691(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  0.400nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032221(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  152nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  21nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Affinity DataEC50:  1.5nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticleMMDB

TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282692(4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  0.400nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282694(4-[(E)-2-(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  989nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282693(4-[(E)-2-(3-Chloro-5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50: >1.00E+3nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  0.5nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032221(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  385nMAssay Description:Transcriptional activation for RXR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044099(4-[(E)-2-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  195nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282691(4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Affinity DataEC50:  15nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044099(4-[(E)-2-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  2.22E+3nMAssay Description:Transcriptional activation for RXR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  13nMAssay Description:Transcriptional activation for RXR alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50044099(4-[(E)-2-(3-Ethyl-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  961nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  0.400nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  102nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Affinity DataEC50:  4nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282692(4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Affinity DataEC50:  0.400nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282694(4-[(E)-2-(3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetr...)
Affinity DataEC50:  21nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Affinity DataEC50:  6nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282693(4-[(E)-2-(3-Chloro-5,5,8,8-tetramethyl-5,6,7,8-tet...)
Affinity DataEC50:  21nMAssay Description:Transcriptional activation for RAR beta receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403249(CHEMBL2114394)
Affinity DataEC50: >6.40E+3nMAssay Description:Transcriptional activation for RXR alpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Displayed 1 to 50 (of 111 total ) | Next | Last >>
Jump to: