TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 0.160nM ΔG°: -55.3kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.6kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -52.3kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -51.9kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -51.9kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.6kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.3kJ/molepH: 7.5 T: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.0kJ/molepH: 7.5 T: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -51.4kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D](Homo sapiens (Human))
Abbott Laboratories
Abbott Laboratories
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/molepH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP1 using [3H]NAD+ by top count scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of PARP2 by top count scintillation countingMore data for this Ligand-Target Pair