TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Matrix metalloprotease-12 in presence of 5 nM acetohydroximateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 20nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 30nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of P110alpha (unknown origin) using L-a-phosphatidylinositol as substrate by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of N-terminal myristoylated P110alpha (unknown origin)-mediated AKT phosphorylation at Ser473 expressed in rat Rat1 cells by ELISAMore data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 50nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of Matrix metalloprotease-12 in presence of 5 nM acetohydroximateMore data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 60nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 60nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 60nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair