Affinity DataKi: 0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00110nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.00280nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0460nM ΔG°: -59.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0520nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0770nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of Eu-DTPA-PEGO-NDP-alpha-MSH-NH2 from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nM ΔG°: -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nM ΔG°: -52.4kJ/mole EC50: 0.710nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
TargetMelanocortin receptor 5(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 0.710nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC5 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC4 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
TargetMelanocortin receptor 5(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 0.760nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC5 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC4 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
TargetMelanocortin receptor 5(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC5 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]substance P from rat NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC4 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]substance P from human NK1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cell membraneMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nM ΔG°: -49.0kJ/mole EC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Displacement of Eu-DTPA-PEGO-NDP-alpha-MSH-NH2 from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMelanocortin receptor 5(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC5 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC4 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center & Research Institute
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC1 receptor expressed in human HCT116 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of Eu-DTPA-PEGOMSH(7) from human MC4R expressed in HEL293 cells after 1 hr by time-resolved fluorescence assayMore data for this Ligand-Target Pair