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Found 87 with Last Name = 'schroeder' and Initial = 'jd'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  300nMAssay Description:Compound was evaluated for inhibition concentration of prostaglandin G/H synthase 2 in human bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50144866(1-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-3-nitroo...)
Affinity DataIC50:  400nMAssay Description:Compound was evaluated for inhibition concentration of prostaglandin G/H synthase 2 in human bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  500nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50024275(CHEMBL2111539)
Affinity DataIC50:  500nMAssay Description:Compound was evaluated for inhibition concentration of prostaglandin G/H synthase 2 in human bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226637(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226637(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226652(4-chlorophenyl 5-methoxy-2-methyl-3-[2-({[3-(nitro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226641(CHEMBL399198 | N-[2,2-dimethyl-3-(nitrooxy)propyl]...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226656(CHEMBL393680 | N-{1,1-bis[(nitrooxy)methyl]-2-(nit...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.20E+3nMAssay Description:Compound was evaluated for inhibition concentration of prostaglandin G/H synthase 2 in human bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226643(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226639(CHEMBL238240 | N-(2-{1-[(4-chlorophenyl)carbonyl]-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50144867(1-[5-(4-Methanesulfonyl-phenyl)-1-(4-methoxy-pheny...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for inhibition concentration of prostaglandin G/H synthase 1 in human bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226653(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112548(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226654(4-chlorophenyl 5-methoxy-2-methyl-3-{2-[({4-[(nitr...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226648(4-chlorophenyl 3-(2-hydroxyethyl)-5-methoxy-2-meth...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112552(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50144867(1-[5-(4-Methanesulfonyl-phenyl)-1-(4-methoxy-pheny...)
Affinity DataIC50:  2.50E+3nMAssay Description:Compound was evaluated for inhibition concentration of prostaglandin G/H synthase 2 in human bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226641(CHEMBL399198 | N-[2,2-dimethyl-3-(nitrooxy)propyl]...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50045400(Acetic acid 2-methanesulfonyl-10,13-dimethyl-3-oxo...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of HIV-1 nuclear regulatory protein TatMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50045403(Acetic acid 2-carbamoyl-3-hydroxy-10,13-dimethyl-1...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of HIV-1 nuclear regulatory protein TatMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50407474(CHEMBL3137917)
Affinity DataIC50:  2.60E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50407473(CHEMBL3137919)
Affinity DataIC50:  2.60E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50407488(CHEMBL3137916)
Affinity DataIC50:  2.70E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50407477(CHEMBL109492)
Affinity DataIC50:  2.80E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226655(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226638(CHEMBL237022 | N-(2-{1-[(4-chlorophenyl)carbonyl]-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50112548(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226657(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226647((2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methy...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50407490(CHEMBL3137910)
Affinity DataIC50:  3.60E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226646(4-chlorophenyl 3-(2-{[(3-hydroxypropyl)sulfonyl]am...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50032828(7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-benzo[e][1...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV-1 nuclear regulatory protein TatMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50032828(7-Chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-benzo[e][1...)
Affinity DataIC50:  4.00E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226653(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Tat(Human immunodeficiency virus type 1 (isolate PCV12...)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50407479(CHEMBL323490)
Affinity DataIC50:  4.50E+3nMAssay Description:The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226657(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50029074(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226655(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226644(2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50226643(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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