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Found 64 with Last Name = 'turchi' and Initial = 'jj'
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241713(CHEMBL4065804)
Affinity DataIC50:  820nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241670(CHEMBL4085647)
Affinity DataIC50:  1.30E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241689(CHEMBL4068522)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241682(CHEMBL4087223)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241715(CHEMBL4080244)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241691(CHEMBL4098283)
Affinity DataIC50:  5.23E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241714(CHEMBL4095853)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461292(US10774063, Compound NG-01-24)
Affinity DataIC50:  7.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241676(CHEMBL4089182)
Affinity DataIC50:  8.40E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241679(CHEMBL4080393)
Affinity DataIC50:  9.10E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241677(CHEMBL4096889)
Affinity DataIC50:  9.10E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241684(CHEMBL4088120)
Affinity DataIC50:  9.10E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241683(CHEMBL4059855)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241673(CHEMBL4083144)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461287(US10774063, Compound NG-01-25 | US10774063, Compou...)
Affinity DataIC50:  1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241695(CHEMBL4061825)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241672(CHEMBL4101139)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241711(CHEMBL4061003)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241706(CHEMBL4077792)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241699(CHEMBL4062874)
Affinity DataIC50:  1.20E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241690(CHEMBL4069536)
Affinity DataIC50:  1.26E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM260646(US9533969, TDRL-505)
Affinity DataIC50:  1.29E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241700(CHEMBL4084551)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241680(CHEMBL4066964)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241681(CHEMBL4086573)
Affinity DataIC50:  1.41E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241675(CHEMBL4078719)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461289(US10774063, Compound TDRL-652)
Affinity DataIC50:  1.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241716(CHEMBL4100999)
Affinity DataIC50:  1.78E+4nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461287(US10774063, Compound NG-01-25 | US10774063, Compou...)
Affinity DataIC50:  1.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM61188(4-[5-(4-methylphenyl)-3-[3-(4-methylphenyl)-1-phen...)
Affinity DataIC50:  2.03E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241671(CHEMBL4064076)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461282(US10774063, Compound TDRL-543)
Affinity DataIC50:  2.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461270(US10774063, Compound TDRL-505 | US10774063, Compou...)
Affinity DataIC50:  2.50E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461288(US10774063, Compound TDRL-557)
Affinity DataIC50:  3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461285(US10774063, Compound TDRL-534)
Affinity DataIC50:  3.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461270(US10774063, Compound TDRL-505 | US10774063, Compou...)
Affinity DataIC50:  3.80E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461286(US10774063, Compound TDRL-556)
Affinity DataIC50:  4.30E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241712(CHEMBL4104617)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241674(CHEMBL4093387)
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461280(US10774063, Compound TDRL-533)
Affinity DataIC50: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241678(CHEMBL4069684)
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241704(CHEMBL4060264)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241705(CHEMBL481937)
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241701(CHEMBL481763)
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50241717(CHEMBL520941)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM260649(US9533969, TDRL-522)
Affinity DataIC50:  5.61E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461276(US10774063, Compound j)
Affinity DataIC50:  6.00E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM260648(US9533969, TDRL-521)
Affinity DataIC50:  7.17E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461272(US10774063, Compound f)
Affinity DataIC50:  7.50E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology

US Patent
LigandPNGBDBM461290(US10774063, Compound NG-01-02)
Affinity DataIC50:  7.55E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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