TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.23E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 1.29E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.41E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 2.03E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 2.50E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of full length human XPA expressed in Sf9 cells assessed as reduction in interaction of XPA with 32P-labeled cisplatin-modified dsDNA by E...More data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
TargetDNA repair protein complementing XP-A cells(Homo sapiens)
Indiana University School of Medicine
Curated by ChEMBL
Indiana University School of Medicine
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 5.61E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 6.00E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 7.17E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent
Affinity DataIC50: 7.50E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research and Technology
US Patent
Indiana University Research and Technology
US Patent