TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Competitive inhibition of human PREP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of human FAP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of human PREP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of human placental DPP4More data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of human recombinant DPP9 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.30E+3nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
Affinity DataKi: 8.40E+3nMAssay Description:Inhibition of human recombinant DPP8 expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.10E+4nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataKi: 1.42E+5nMAssay Description:Competitive inhibition of human recombinant DPP4 using AP-pNA as substrate preincubated for 30 mins followed by substrate addition measured after 30 ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human DPP4 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human DPP9 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human DPP4 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human placental DPP4 at pH 2More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.700nMpH: 7.4Assay Description:Inhibition of DDP4 at pH 7.4 preincubated with alpha-chymotrypsin up to 8 hrsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1nMpH: 2.0Assay Description:Inhibition of DDP4 at pH 2 preincubated for 10 minsMore data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human DPP8 expressed in HEK293 cells using Ala-Pro-p-nitroanilide hydrochloride salt as substrate preincubated for 10 mins prior to add...More data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School Of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.5nMpH: 2.0Assay Description:Inhibition of DDP4 at pH 2 preincubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]-exendin (9 to 39) from human GLP-1R expressed in African green monkey COS7 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Tufts University School of Medicine
Curated by ChEMBL
Tufts University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human placental DPP4 at pH 2More data for this Ligand-Target Pair