Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mi...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 194nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 233nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.34E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 148nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 92nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 57nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.92E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Activity at human CaSR expressed in HEK293 cells assessed as calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 370nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 870nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 620nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair