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Found 1386 with Last Name = 'nacro' and Initial = 'k'
TargetProtein kinase C alpha type(Bos taurus (bovine))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  0.200nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50057512((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-...)
Affinity DataKi:  0.200nMAssay Description:Binding Affinity against protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104371(US8575186, 134/183/184 | US8575186, 199 | US857518...)
Affinity DataKi:  0.260nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104408(US8575186, 171/172 | US8575186, 188)
Affinity DataKi:  0.280nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104331(US8575186, 177 | US8575186, 178 | US8575186, 94/16...)
Affinity DataKi:  0.280nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104378(US8575186, 141)
Affinity DataKi:  0.290nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104467(US8575186, 230/231 | US8575186, 247)
Affinity DataKi:  0.310nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104382(US8575186, 145)
Affinity DataKi:  0.310nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364980(CHEMBL1950775)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364980(CHEMBL1950775)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104331(US8575186, 177 | US8575186, 178 | US8575186, 94/16...)
Affinity DataKi:  0.320nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364981(CHEMBL1950776)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104361(US8575186, 124)
Affinity DataKi:  0.330nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104371(US8575186, 134/183/184 | US8575186, 199 | US857518...)
Affinity DataKi:  0.350nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104477(US8575186, 240/241 | US8575186, 257)
Affinity DataKi:  0.350nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364981(CHEMBL1950776)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104408(US8575186, 171/172 | US8575186, 188)
Affinity DataKi:  0.360nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364981(CHEMBL1950776)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364980(CHEMBL1950775)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104331(US8575186, 177 | US8575186, 178 | US8575186, 94/16...)
Affinity DataKi:  0.370nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104402(US8575186, 165/166 | US8575186, 182)
Affinity DataKi:  0.410nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104321(US8575186, 250 | US8575186, 251 | US8575186, 84/23...)
Affinity DataKi:  0.420nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104371(US8575186, 134/183/184 | US8575186, 199 | US857518...)
Affinity DataKi:  0.420nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104475(US8575186, 238/239 | US8575186, 255)
Affinity DataKi:  0.430nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104454(US8575186, 217/218 | US8575186, 234)
Affinity DataKi:  0.460nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104376(US8575186, 139)
Affinity DataKi:  0.470nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104360(US8575186, 123)
Affinity DataKi:  0.470nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104430(US8575186, 193/194 | US8575186, 210)
Affinity DataKi:  0.5nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104456(US8575186, 219/220 | US8575186, 236)
Affinity DataKi:  0.5nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104302(US8575186, 203 | US8575186, 204 | US8575186, 65/18...)
Affinity DataKi:  0.5nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104462(US8575186, 225/226 | US8575186, 242)
Affinity DataKi:  0.530nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104446(US8575186, 209/215/216 | US8575186, 231 | US857518...)
Affinity DataKi:  0.530nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104377(US8575186, 140)
Affinity DataKi:  0.560nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104458(US8575186, 221/222 | US8575186, 238)
Affinity DataKi:  0.560nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104320(US8575186, 228 | US8575186, 229 | US8575186, 83/21...)
Affinity DataKi:  0.570nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104479(US8575186, 242/243 | US8575186, 259)
Affinity DataKi:  0.580nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104302(US8575186, 203 | US8575186, 204 | US8575186, 65/18...)
Affinity DataKi:  0.590nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104464(US8575186, 227)
Affinity DataKi:  0.680nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104299(US8575186, 205 | US8575186, 206 | US8575186, 62/18...)
Affinity DataKi:  0.680nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104444(US8575186, 207/208 | US8575186, 224)
Affinity DataKi:  0.690nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104339(US8575186, 102)
Affinity DataKi:  0.710nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104346(US8575186, 109)
Affinity DataKi:  0.720nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104438(US8575186, 201/202 | US8575186, 218)
Affinity DataKi:  0.720nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104335(US8575186, 179 | US8575186, 180 | US8575186, 98/16...)
Affinity DataKi:  0.740nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104364(US8575186, 127/199/200 | US8575186, 215 | US857518...)
Affinity DataKi:  0.75nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104422(US8575186, 185/186 | US8575186, 202)
Affinity DataKi:  0.770nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104446(US8575186, 209/215/216 | US8575186, 231 | US857518...)
Affinity DataKi:  0.800nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50365005(CHEMBL1950777)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104402(US8575186, 165/166 | US8575186, 182)
Affinity DataKi:  0.810nMAssay Description:The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM50364978(CHEMBL1950773)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]LSD from human 5-HT6 serotonin receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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