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Found 376 with Last Name = 'yamatsu' and Initial = 'k'
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010542(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  0.770nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  0.850nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010542(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  1nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010538(2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  1.20nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010537(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010535(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataKi:  1.40nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010536(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  1.60nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010545(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataKi:  1.70nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010534(2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-pro...)
Affinity DataKi:  1.90nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010536(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  2.80nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  3nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010535(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataKi:  3.30nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010545(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataKi:  3.90nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010534(2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-pro...)
Affinity DataKi:  4.5nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010538(2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  7.20nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  7.70nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010537(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  9.20nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010545(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataKi:  18nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010538(2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  24nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010534(2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-pro...)
Affinity DataKi:  27nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010542(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  29nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010537(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  30nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010536(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataKi:  39nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010535(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataKi:  54nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  630nMAssay Description:Binding affinities against Opioid receptor delta 1 of guinea pig brain membrane using [3H]-DPDPE as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Mus musculus (Mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  1.55E+3nMAssay Description:Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  0.00700nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  0.0600nMAssay Description:Evaluated for inhibitory activity against Opioid receptor kappa 1 of rabbit vas deferens (RVD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010532(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  0.130nMAssay Description:Evaluated for inhibitory activity against Opioid receptor delta 1 of mouse vas deferens (MVD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010538(2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  0.200nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010534(2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-pro...)
Affinity DataIC50:  0.300nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010545(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataIC50:  0.5nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010535(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataIC50:  0.5nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM9409(CHEMBL299708 | N-[2-(1-benzylpiperidin-4-yl)ethyl]...)
Affinity DataIC50:  0.560nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM9409(CHEMBL299708 | N-[2-(1-benzylpiperidin-4-yl)ethyl]...)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  0.680nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  0.680nMAssay Description:Inhibitory concentration of the compound was determined in vitro and ex vivo for anti-AChE activity in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  0.690nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010540(2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-pro...)
Affinity DataIC50:  0.700nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010546(2-{5-Guanidino-2-[5-guanidino-2-({2-[2-(2-{2-[3-(4...)
Affinity DataIC50:  1.10nMAssay Description:Evaluated for inhibitory activity against Opioid receptor kappa 1 of rabbit vas deferens (RVD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50004016(CHEMBL138107 | CHEMBL544159 | N-(2-(2-(1-benzylpip...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50004016(CHEMBL138107 | CHEMBL544159 | N-(2-(2-(1-benzylpip...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010542(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataIC50:  1.30nMAssay Description:Evaluated for inhibitory activity against Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eisai

Curated by ChEMBL
LigandPNGBDBM50010536(2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinities against Opioid receptor mu 1 of guinea pig brain membrane using [3H]-DAGO as the radioligand using competition binding assays.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50029933(2-[3-(1-Benzyl-piperidin-4-yl)-propyl]-5,6-dimetho...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50029944(5,6-Dimethoxy-2-[1-(3-methyl-benzyl)-piperidin-4-y...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50004007(2-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-1,3-dioxo-2,...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50010535(2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4...)
Affinity DataIC50:  2.30nMAssay Description:Evaluated for inhibitory activity against Opioid receptor kappa 1 of rabbit vas deferens (RVD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Eisai

Curated by ChEMBL
LigandPNGBDBM50004001(5-Benzoyl-2-[2-(1-benzyl-piperidin-4-yl)-ethyl]-is...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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