Affinity DataKi: 0.00200nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.00500nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.00800nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0120nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0160nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of HIV-1 wildtype protease using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition mea...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of HIV-1 protease R8Q mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition m...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition of HIV-1 protease V82A mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of HIV-1 protease I54M mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of wild type HIV-1 NL4-3 protease expressed in Escherichia coli Rosetta (DE3)pLysS using Ac-Thr-Ile-Nle-Nle-Gln-Arg-NH2 as substrate by fl...More data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Inhibition of HIV-1 protease D30N mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Inhibition of HIV-1 protease I50V mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 122nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 144nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 164nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 783nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataKi: 1.46E+3nMAssay Description:Inhibition of recombinant beta-secretase 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of ETA receptor in human SK-N-MC cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of neuropeptide Y1 receptor in human SK-N-MC cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of neuropeptide Y1 receptor in human SK-N-MC cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 423nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 878nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.25E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.55E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.85E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Agonist activity at human delta opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.15E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair