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Found 39 with Last Name = 'otterbein' and Initial = 'lr'
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194411((S)-2,3-dichloro-N-(1-(dimethylamino)-1-oxo-3-phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  7nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194415(2,3-dichloro-N-((1R,2R)-1-hydroxy-2,3-dihydro-1H-i...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194414((S)-2-chloro-N-(1-(dimethylamino)-1-oxo-3-phenylpr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  18nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194420((S)-2,3-dibromo-N-(1-(dimethylamino)-1-oxo-3-pheny...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  23nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194417((S)-2-bromo-N-(1-(dimethylamino)-1-oxo-3-phenylpro...)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM24363(2-chloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194410(2,3-dichloro-N-((1R,2R)-6-fluoro-1-hydroxy-2,3-dih...)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50065954((S)-5-chloro-N-(1-(dimethylamino)-1-oxo-3-phenylpr...)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  58nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50136437(5-Chloro-1H-indole-2-carboxylic acid (2-oxo-1,2,3,...)
Affinity DataIC50:  86nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194418(2,3-dichloro-N-((1R,2R)-6-chloro-1-hydroxy-2,3-dih...)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM24361(2,3-dichloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3...)
Affinity DataIC50:  132nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194423(2,3-dichloro-N-(2,3-dihydro-1H-inden-2-yl)-4H-thie...)
Affinity DataIC50:  197nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  280nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194412(2-CHLORO-N-[(1R,2R)-1-HYDROXY-2,3-DIHYDRO-1H-INDEN...)
Affinity DataIC50:  319nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194424((S)-3-chloro-N-(1-(methylamino)-1-oxo-3-phenylprop...)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  400nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194413((S)-2-chloro-N-(1-(methylamino)-1-oxo-3-phenylprop...)
Affinity DataIC50:  577nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194422(2-chloro-N-(2,3-dihydro-1H-inden-2-yl)-6H-thieno[2...)
Affinity DataIC50:  806nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Escherichia coli)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50:  2.10E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194421((S)-N-(1-(dimethylamino)-1-oxo-3-phenylpropan-2-yl...)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50:  3.30E+3nM Kd:  1.90E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50:  4.70E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50:  6.40E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Haemophilus influenzae)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50:  7.80E+3nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194416((S)-2,3-dibromo-N-(1-(dimethylamino)-1-oxo-3-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50194419((S)-2,3-dibromo-N-(1-(dimethylamino)-1-oxo-3-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50:  1.50E+4nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50:  4.00E+4nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM92472(Sulfonamide, 3)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM50365075(CHEMBL1951164 | Sulfonamide, 2)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM92473(Sulfonamide, 4)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional protein GlmU(Staphylococcus aureus)
Astrazeneca

LigandPNGBDBM50365062(CHEMBL1951072 | Sulfonamide, 1)
Affinity DataIC50: >2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed