Affinity DataKi: 0.100nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.224nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University of Pisa
Curated by PDSP Ki Database
University of Pisa
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University of Pisa
Curated by PDSP Ki Database
University of Pisa
Curated by PDSP Ki Database
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]N-methylscopolamine chloride from human cloned muscarinic M2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.389nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.407nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1B adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.427nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.589nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Binding affinity against Opioid receptor mu 1 in Guinea pig brain membranes using [3H]DAMGOMore data for this Ligand-Target Pair
Affinity DataKi: 0.832nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Binding affinity against Opioid receptor mu 1 in Guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Non-competitive inhibition of electric eel AChE assessed as enzyme-inhibitor complex using p-nitrophenyl acetate as substrate by Lineweaver-Burk plot...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Non-competitive inhibition of electric eel AChE assessed as enzyme-substrate-inhibitor complex using p-nitrophenyl acetate as substrate by Lineweaver...More data for this Ligand-Target Pair
Affinity DataKi: 1.24nMAssay Description:Binding affinity against Delta Opioid receptor in Guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of NG 108-15 binding to Muscarinic acetylcholine receptor M4Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.49nMAssay Description:Competitive inhibition constant for AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University of Pisa
Curated by PDSP Ki Database
University of Pisa
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-inhibitor complex using butyrylthiocholine iodide as substrate measured...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair