Compile Data Set for Download or QSAR
maximum 50k data
Found 122 with Last Name = 'le bret' and Initial = 'm'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174413(2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004235((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004235((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004227(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against Fibroblast growth factor receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004227(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004227(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174413(2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004235((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against Fibroblast growth factor receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004227(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174412(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087419((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50004235((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087419((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174412(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087427((E)-8-hydroxy-2-(3-hydroxy-4-methoxystyryl)quinoli...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50145369(2-(3,4-Dihydroxy-phenylcarbamoyl)-8-hydroxy-quinol...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065796((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087429((E)-2-(3,5-dibromo-4-hydroxystyryl)-8-hydroxyquino...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087431(2-[2-(4-Acetylamino-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174410(1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087432(8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087429((E)-2-(3,5-dibromo-4-hydroxystyryl)-8-hydroxyquino...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174408(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against Fibroblast growth factor receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174410(1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087431(2-[2-(4-Acetylamino-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087426(2-(3,4-dihydroxyphenethyl)-8-hydroxyquinoline-7-ca...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50145363(8-Hydroxy-2-(2,3,4-trihydroxy-benzylcarbamoyl)-qui...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087435((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087435((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087432(8-Hydroxy-2-[2-(4-nitro-phenyl)-vinyl]-quinoline-7...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087419((E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyqui...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174411(CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087430((E)-2-(2-(furan-2-yl)vinyl)-8-hydroxyquinoline-7-c...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in 3'-end- processing was tested in CEM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174407(CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174408(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against Platelet-derived growth factor receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065793(8-Hydroxy-2-[(E)-2-(3,4,5-trihydroxy-phenyl)-vinyl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rous sarcoma virus (RSV) Integrase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087421(8-Hydroxy-2-((E)-styryl)-quinoline-7-carboxylic ac...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087420((E)-2-(4-aminostyryl)-8-hydroxyquinoline-7-carboxy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase in strand transfer(integration)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065796((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of rous sarcoma virus (RSV) Integrase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087426(2-(3,4-dihydroxyphenethyl)-8-hydroxyquinoline-7-ca...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50087426(2-(3,4-dihydroxyphenethyl)-8-hydroxyquinoline-7-ca...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174411(CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065796((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro inhibition of recombinant integrase activity in a standard 3'-processing assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065796((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against Integrase in 3'-end- processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Cnrs Umr 8532

Curated by ChEMBL
LigandPNGBDBM50065796((E)-2-(3,4-dihydroxystyryl)-8-hydroxyquinoline-7-c...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human immunodeficiency virus-1 (HIV-1) integrase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174408(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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