BindingDB PrimarySearch

Found 60 with Last Name = 'sanhaji' and Initial = 'm'

Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

IC50: 0.300nMAssay Description:Inhibition of GST-tagged human SIK2 autophosphorylation measured after 30 mins in presence of [gamma33P]ATP by Western blot analysisMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601534(CHEMBL4539742)

IC50: 1nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50148921(CHEMBL3770443)

IC50: 4.40nMAssay Description:Inhibition of GST-tagged human SIK2 autophosphorylation measured after 30 mins in presence of [gamma33P]ATP by Western blot analysisMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601534(CHEMBL4539742)

IC50: 6nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601534(CHEMBL4539742)

IC50: 21nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 22nMAssay Description:Inhibition of human SIK3 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 41nMAssay Description:Inhibition of human PAK2 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 48nMAssay Description:Inhibition of human SIK2 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 55nMAssay Description:Inhibition of human SIK1 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 3(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 140nMAssay Description:Inhibition of human PAK3 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 210nMAssay Description:Inhibition of human MAP4K5 (KHS1) by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase NLK(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 250nMAssay Description:Inhibition of human NLK by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)

IC50: 460nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 516nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK1 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 580nMAssay Description:Inhibition of human PAK1 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 830nMAssay Description:Inhibition of human MAP2K4 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM192712(HG-9-91-01 (1))

IC50: 920nMAssay Description:Inhibition of GST fused recombinant SIK1 (unknown origin) in human HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser162 incubated for 1...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)

IC50: 1.10E+3nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase N3(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 1.40E+3nMAssay Description:Inhibition of human PKN3 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 26(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 1.60E+3nMAssay Description:Inhibition of human MST4 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Maternal embryonic leucine zipper kinase(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 2.20E+3nMAssay Description:Inhibition of human MELK by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Angiopoietin-1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 3.10E+3nMAssay Description:Inhibition of human TIE2 by radiometric PanQinase activity assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase NLK(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 3.10E+3nMAssay Description:Inhibition of full length C-terminal nanoLuc-tagged human NLK expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in prese...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM192712(HG-9-91-01 (1))

IC50: 3.50E+3nMAssay Description:Inhibition of SIK2 (unknown origin) assessed as enzyme remaining activity by scanMAX kinase assayMore data for this Ligand-Target Pair

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Angiopoietin-1 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 6.00E+3nMAssay Description:Inhibition of full length C-terminal nanoLuc-tagged human TIE2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM192712(HG-9-91-01 (1))

IC50: 6.60E+3nMAssay Description:Inhibition of GST fused recombinant SIK2 (unknown origin) in human HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser162 incubated for 1...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase N3(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 6.70E+3nMAssay Description:Inhibition of full length C-terminal nanoLuc-tagged human PKN3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601537(CHEMBL5194644)

IC50: 7.00E+3nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50148921(CHEMBL3770443)

IC50: 9.00E+3nMAssay Description:Inhibition of SIK2 (unknown origin) assessed as enzyme remaining activity by scanMAX kinase assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601539(CHEMBL5189489)

IC50: 9.00E+3nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM192712(HG-9-91-01 (1))

IC50: 9.60E+3nMAssay Description:Inhibition of GST fused recombinant SIK3 (unknown origin) in human HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser162 incubated for 1...More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 1.30E+4nMAssay Description:Inhibition of full length C-terminal nanoLuc-tagged human MAP4K5 (KHS1) expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hr...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601540(CHEMBL5194766)

IC50: 1.40E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50148921(CHEMBL3770443)

IC50: 2.40E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase 26(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 3.40E+4nMAssay Description:Inhibition of full length nanoLuc-tagged human MST4 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in presence of tra...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM192716(US11725011, Compound YKL-05-99 | YKL-05-099 (5))

IC50: 4.00E+4nMAssay Description:Inhibition of SIK2 (unknown origin) assessed as enzyme remaining activity by scanMAX kinase assayMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601544(CHEMBL5175296)

IC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601540(CHEMBL5194766)

IC50: 6.50E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601545(CHEMBL5187267)

IC50: 8.00E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601535(CHEMBL5180834)

IC50: 8.30E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601542(CHEMBL5169576)

IC50: 8.40E+4nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601536(CHEMBL5200656)

IC50: 1.17E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601546(CHEMBL5179229)

IC50: 1.20E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 1.27E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601539(CHEMBL5189489)

IC50: 1.39E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3(Homo sapiens)
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601541(CHEMBL5193137)

IC50: 1.53E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK3 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601537(CHEMBL5194644)

IC50: 1.60E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50601538(CHEMBL5090394)

IC50: 1.80E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM50148921(CHEMBL3770443)

IC50: 3.09E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL

BDBM192716(US11725011, Compound YKL-05-99 | YKL-05-099 (5))

IC50: 3.44E+5nMAssay Description:Inhibition of full length N-terminal nanoLuc-tagged human SIK2 expressed in HEK293 cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pres...More data for this Ligand-Target Pair

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Displayed 1 to 50 (of 60 total ) | Next | Last >>

Filter my 60 hits

Targets 13▿
- Serine/threonine-protein kinase SIK2 24
- Serine/threonine-protein kinase SIK3 17
- Serine/threonine-protein kinase SIK1 4
- Angiopoietin-1 receptor 2
- Serine/threonine-protein kinase NLK 2
- Mitogen-activated protein kinase kinase kinase kinase 5 2
- Serine/threonine-protein kinase 26 2
- Serine/threonine-protein kinase N3 2
- Dual specificity mitogen-activated protein kinase kinase 4 1
- Serine/threonine-protein kinase PAK 1 1
- Serine/threonine-protein kinase PAK 2 1
- Maternal embryonic leucine zipper kinase 1
- Serine/threonine-protein kinase PAK 3 1
Publications 1▿
- J Med Chem 64: 8142-8160 (2021) 60
Institutions 1▿
- Johann Wolfgang Goethe University 60
Affinity: 0.30 to 4.4E+6 nM▿
- IC50 60
- Affinity ≤ nM
Xtal structures: 5
Docked structures: 0
Catalog Cmpds: 6