TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by e-NOS from HUVECcellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human neuronal nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The compound was tested in vitro for inhibition against 5-lipoxygenase in intact human neutrophilsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by e-NOS from HUVECcellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against human neuronal nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca Charnwood
Curated by ChEMBL
Astrazeneca Charnwood
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by e-NOS from HUVECcellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human neuronal nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:The compound was tested in vitro for inhibition against 5-lipoxygenase in intact human neutrophilsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against human endothelial nitiric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair