TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 18.4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 54.2nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 254nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 618nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]rosiglitazone from human PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (1 to 40) hydrolysis preincubated for 10 mins measured after 30 mins by spectrophotometer a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ECE1-mediated amyloid beta hydrolysis after 45 mins by fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ACE2-mediated amyloid beta hydrolysis using Mca-Tyr-Val-Ala-Asp-Pro-Ala-Lys-(DNP)-OH as substrate after 20 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP13-mediated amyloid beta hydrolysis after 10 mins by fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP1-mediated amyloid beta hydrolysis using DNP-Pro-Cha-Gly- Cys(Me)-His-Ala- Lys(n-Me-Abz)-NH2 as substrate after 40...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant TACE-mediated amyloid beta hydrolysis after 5 mins by fluorimetry assayMore data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Induction of human recombinant IDE-mediated insulin hydrolysis preincubated for 10 mins measured after 30 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 1.01E+3nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataEC50: 1.19E+3nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataEC50: 1.58E+3nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 977nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 98nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataEC50: 757nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857
Curated by ChEMBL
Spot-Ea3857
Curated by ChEMBL
Affinity DataEC50: 1.82E+3nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataEC50: 8.39E+3nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair