TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
University of Ioannina
Curated by ChEMBL
University of Ioannina
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]-D-Tyr6-His5-GnRH from recombinant human GnRH receptor expressed in HEK293 cell membrane measured after 16 to 19 hrs by gamma c...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
University of Ioannina
Curated by ChEMBL
University of Ioannina
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:Displacement of [125I]-D-Tyr6-His5-GnRH from recombinant human GnRH receptor expressed in HEK293 cell membrane measured after 16 to 19 hrs by gamma c...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
University of Ioannina
Curated by ChEMBL
University of Ioannina
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]-DTrp6-LHRH from human GnRH-R by radioligand binding assayMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
University of Ioannina
Curated by ChEMBL
University of Ioannina
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]-D-Tyr6-His5-GnRH from recombinant human GnRH receptor expressed in HEK293 cell membrane measured after 16 to 19 hrs by gamma c...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
University of Ioannina
Curated by ChEMBL
University of Ioannina
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Displacement of [125I]-D-Tyr6-His5-GnRH from recombinant human GnRH receptor expressed in HEK293 cell membrane measured after 16 to 19 hrs by gamma c...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
University of Ioannina
Curated by ChEMBL
University of Ioannina
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-D-Tyr6-His5-GnRH from recombinant human GnRH receptor expressed in HEK293 cell membrane measured after 16 to 19 hrs by gamma c...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of N6-[3H]Cyclohexyladenosine from adenosine A1 receptor in rat brain membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Displacement of N6-[3H]Cyclohexyladenosine from adenosine A1 receptor in rat brain membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Displacement of N6-[3H]Cyclohexyladenosine from adenosine A1 receptor in rat brain membranes after 60 minsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK5 (M1 to P292 residues)/N-terminal His6-tagged p25NCK (A104 to R307 residue...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of CDK1/CyclinB (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to M298 residues)/CyclinA2 (M1 to V432 residues) expressed in Sf9 insect c...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK9 (M1 to F372 residues)/N-terminal His6-tagged CyclinT1 (M1 to K726 residue...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to M298 residues)/CyclinA2 (M1 to V432 residues) expressed in Sf9 insect c...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK5 (M1 to P292 residues)/N-terminal His6-tagged p25NCK (A104 to R307 residue...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK9 (M1 to F372 residues)/N-terminal His6-tagged CyclinT1 (M1 to K726 residue...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/CyclinB1 (M1 to V433 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/CyclinB1 (M1 to V433 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/CyclinD1 (Q4 to I295 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK1/CyclinB (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/CyclinD1 (Q4 to I295 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 4.78E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 6.21E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 6.33E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 7.19E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
University of Kwazulu-Natal (Ukzn)
Curated by ChEMBL
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of MT-stimulated EG5 ATPase activity (unknown origin) by pyruvate kinase/lactate dehydrogenase enzyme coupled photometric assayMore data for this Ligand-Target Pair