BindingDB PrimarySearch

Found 1793 with Last Name = 'fan' and Initial = 'r'

Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

Ki: 0.100nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581204(CHEMBL5076637)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581191(CHEMBL5070876)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581209(CHEMBL4650755)

Ki: 0.126nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581203(CHEMBL5074599)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581192(CHEMBL5091461)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581203(CHEMBL5074599)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581185(CHEMBL5076558)

Ki: 0.158nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581187(CHEMBL5077161)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581189(CHEMBL5075132)

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Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581209(CHEMBL4650755)

Ki: 0.158nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M2 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581193(CHEMBL5084383)

Ki: 0.200nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581203(CHEMBL5074599)

Ki: 0.200nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M2 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581202(CHEMBL5090464)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581190(CHEMBL5076266)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581199(CHEMBL5090179)

Ki: 0.251nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581200(CHEMBL5084829)

Ki: 0.316nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581201(CHEMBL5085717)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581188(CHEMBL5076680)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581186(CHEMBL5088742)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581198(CHEMBL5086769)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581185(CHEMBL5076558)

Ki: 0.398nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581185(CHEMBL5076558)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581183(CHEMBL5087564)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581206(CHEMBL5076886)

Ki: 0.501nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581195(CHEMBL5085166)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581206(CHEMBL5076886)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581205(CHEMBL5077424)

Ki: 0.631nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581205(CHEMBL5077424)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581184(CHEMBL5094110)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581181(CHEMBL5086895)

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Histone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

BDBM50193709(CHEMBL3911017)

Ki: 0.700nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair

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3D Structure (crystal)

Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581179(CHEMBL5078680)

Ki: 0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581210(IPRATROPIUM | Ipratropium | Ipratropium cation | I...)

Ki: 0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M2 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581196(CHEMBL5086272)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581210(IPRATROPIUM | Ipratropium | Ipratropium cation | I...)

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Neurotensin receptor type 1(Homo sapiens (Human))
University of Montpellier

Curated by ChEMBL

BDBM50048908(CHEMBL415788)

Ki: 1.10nMAssay Description:Displacement of 125I-[Tyr3]-NT from human NTS1 receptor expressed in CHOK1 cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581180(CHEMBL5081214)

Ki: 1.30nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581182(CHEMBL5080391)

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Histone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

BDBM50193663(CHEMBL3929944)

Ki: 2nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM325637(US9636336, Example 28 | US9636336, Example 94 | US...)

Ki: 2.5nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM325637(US9636336, Example 28 | US9636336, Example 94 | US...)

Ki: 2.51nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581197(CHEMBL5077250)

Ki: 3.20nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 9(Homo sapiens (Human))
Celgene

Curated by ChEMBL

BDBM50364378(CHEMBL1950289)

Ki: 6.20nMAssay Description:Inhibition of hexa-His-tagged JNK2 expressed in baculoviral system using GST-tagged cJun as substrate preincubated for 15 mins prior ATP addition mea...More data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)

Ki: 6.30nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM325621(US9636336, Example 11 | US9636336, Example 65 | US...)

Ki: 6.31nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Neurotensin receptor type 2(Homo sapiens (Human))
University of Montpellier

Curated by ChEMBL

BDBM50048908(CHEMBL415788)

Ki: 6.60nMAssay Description:Displacement of 125I-[Tyr3]-NT from human NTS2 receptor expressed in human 1321N1 cell membranes after 30 mins by gamma counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581207(CHEMBL5074216)

Ki: 7.90nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581194(CHEMBL5069430)

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Muscarinic acetylcholine receptor M3(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL

BDBM50581207(CHEMBL5074216)

Ki: 7.94nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

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Displayed 1 to 50 (of 1793 total ) | Next | Last >>

Filter my 1793 hits

Targets 79▿
- 5'-nucleotidase 396
- Glucocorticoid receptor 203
- cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D 98
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 88
- Androgen receptor 70
- Muscarinic acetylcholine receptor M3 63
- Oxysterols receptor LXR-beta 51
- Oxysterols receptor LXR-alpha 51
- Estrogen receptor 42
- Histone-lysine N-methyltransferase EZH2 41
- Mitogen-activated protein kinase 8 40
- Mitogen-activated protein kinase 14 39
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B 36
- Neurotensin receptor type 1 33
- Beta-3 adrenergic receptor 32
- Hepatocyte growth factor receptor 30
- Beta-1 adrenergic receptor 27
- Receptor-type tyrosine-protein kinase FLT3 [564-960] 27
- Aurora kinase B [1-341] 27
- Tyrosine-protein kinase SYK [342-635] 27
- Mitogen-activated protein kinase 9 26
- Mitogen-activated protein kinase 10 25
- Progesterone receptor 23
- 72 kDa type IV collagenase 21
- Aminopeptidase N 21
- Beta-2 adrenergic receptor 20
- Tyrosine-protein phosphatase non-receptor type 1 19
- Oxysterols receptor LXR-beta [154-461] 17
- Oxysterols receptor LXR-alpha [197-447] 17
- Neurotensin receptor type 2 15
- Integrase 12
- Vasopressin V2 receptor 11
- Cytochrome P450 2C8 10
- Epidermal growth factor receptor 9
- Cytochrome P450 3A4 9
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 8
- Isocitrate dehydrogenase [NADP] cytoplasmic 8
- Cytochrome P450 2C9 7
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5
- Protease 5
- Lysosomal acid glucosylceramidase 5
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5
- Vasopressin V1a receptor 4
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 4
- cGMP-specific 3',5'-cyclic phosphodiesterase 3
- Cytochrome P450 1A2 3
- Cytochrome P450 2C19 3
- cGMP-dependent 3',5'-cyclic phosphodiesterase 3
- Muscarinic acetylcholine receptor M2 3
- Vascular endothelial growth factor receptor 2 3
- Cytochrome P450 2D6 3
- Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 2
- High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A 2
- Oxytocin receptor 2
- Tyrosine-protein kinase receptor UFO 2
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 2
- Acetylcholinesterase 2
- Caspase-1 2
- Angiopoietin-1 receptor 2
- High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 2
- Glutamate receptor ionotropic, kainate 2 2
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A 2
- Proto-oncogene tyrosine-protein kinase receptor Ret 2
- Vascular endothelial growth factor receptor 3 2
- Cytochrome P450 2B6 2
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 2
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 2
- Vascular endothelial growth factor receptor 1 2
- Receptor-type tyrosine-protein kinase FLT3 1
- Mast/stem cell growth factor receptor Kit 1
- Mitogen-activated protein kinase 3 1
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B 1
- Tyrosine-protein kinase receptor TYRO3 1
- Dual specificity protein kinase CLK4 1
- Tyrosine-protein kinase Mer 1
- Fibroblast growth factor receptor 1 1
- Estrogen receptor beta 1
- MAP kinase-interacting serine/threonine-protein kinase 1 1
- Potassium voltage-gated channel subfamily H member 2 1
- ...
Publications 33▿
- US Patent US11325938 (2022) 213
- US Patent US11377469 (2022) 135
- J Med Chem 60: 5193-5208 (2017) 119
- J Med Chem 61: 7767-7784 (2018) 113
- J Med Chem 64: 9100-9119 (2021) 108
- US Patent US11124537 (2021) 103
- Bioorg Med Chem Lett 20: 521-5 (2010) 102
- J Med Chem 57: 793-816 (2014) 101
- J Med Chem 62: 6751-6764 (2019) 95
- Bioorg Med Chem Lett 22: 1427-32 (2012) 88
- US Patent US10155751 (2018) 81
- J Med Chem 63: 10433-10459 (2020) 51
- Bioorg Med Chem Lett 12: 2957-61 (2002) 45
- Bioorg Med Chem Lett 22: 1433-8 (2012) 44
- J Med Chem 47: 6435-8 (2004) 43
- Bioorg Med Chem 17: 3053-60 (2009) 42
- J Med Chem 59: 8306-25 (2016) 41
- Eur J Med Chem 192: (2020) 35
- Bioorg Med Chem Lett 12: 2963-7 (2002) 34
- J Med Chem 51: 7161-8 (2008) 34
- J Med Chem 58: 7785-95 (2015) 32
- Eur J Med Chem 212: (2021) 21
- J Med Chem 60: 10026-10046 (2017) 20
- J Nat Prod 83: 814-824 (2020) 19
- Bioorg Med Chem Lett 16: 954-9 (2006) 17
- J Med Chem 60: 3303-3313 (2017) 16
- ACS Med Chem Lett 3: 850-855 (2012) 8
- Bioorg Med Chem Lett 30: (2020) 5
- J Med Chem 55: 6762-75 (2012) 5
- Drug Metab Dispos 41: 230-7 (2012) 5
- J Nat Prod 67: 1882-5 (2004) 2
- Nature 402: 297-301 (1999) 2
- J Med Chem 57: 10366-82 (2014) 2
Institutions 20▿
- Oric Pharmaceuticals 710
- Chiesi Farmaceutici 229
- Wyeth Research 173
- Celgene 132
- Bristol-Myers Squibb 119
- Wyeth Pharmaceuticals 102
- Boehringer Ingelheim International 81
- Shandong University 42
- Pfizer 41
- China Pharmaceutical University 35
- University Of Montpellier 32
- Sun Yat-Sen University 21
- Peking University 19
- University of Montpellier 16
- TBA 8
- Universit£ 7
- Onyx Pharmaceuticals 5
- Temple University 5
- University of Bristol 2
- Instituto De Qu£Mica Da Universidade Estadual Paulista 2
Affinity: 0.020 to 8.1E+5 nM▿
- Ki 82
- IC50 1468
- Kd 2
- EC50 273
- Affinity ≤ nM
Xtal structures: 25
Docked structures: 1
Catalog Cmpds: 53